Chemical force microscopy of chemical and biological interactions
نویسندگان
چکیده
منابع مشابه
Chemical Force Microscopy Nanoscale Probing of Fundamental Chemical Interactions
Intermolecular forces impact a wide spectrum of problems in condensed phases: from molecular recognition, self-assembly, and protein folding at the molecular and nanometer scale, to interfacial fracture, friction, and lubrication at a macroscopic length scale. Understanding these phenomena, regardless of the length scale, requires fundamental knowledge of the magnitude and range of underlying w...
متن کاملEvaluation of Chemical Interactions between Small Molecules in the Gas Phase Using Chemical Force Microscopy
Chemical force microscopy analyzes the interactions between various chemical/biochemical moieties in situ. In this work we examined force-distance curves and lateral force to measure the interaction between modified AFM tips and differently functionalized molecular monolayers. Especially for the measurements in gas phase, we investigated the effect of humidity on the analysis of force-distance ...
متن کاملNanoscale chemical imaging by photoinduced force microscopy.
Correlating spatial chemical information with the morphology of closely packed nanostructures remains a challenge for the scientific community. For example, supramolecular self-assembly, which provides a powerful and low-cost way to create nanoscale patterns and engineered nanostructures, is not easily interrogated in real space via existing nondestructive techniques based on optics or electron...
متن کاملPredicting Biological Functions of Compounds Based on Chemical-Chemical Interactions
Given a compound, how can we effectively predict its biological function? It is a fundamentally important problem because the information thus obtained may benefit the understanding of many basic biological processes and provide useful clues for drug design. In this study, based on the information of chemical-chemical interactions, a novel method was developed that can be used to identify which...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Surface and Interface Analysis
سال: 2006
ISSN: 0142-2421,1096-9918
DOI: 10.1002/sia.2374